ADAR1 IS A PROMISING RISK STRATIFICATION BIOMARKER OF REMNANT LIVER RECURRENCE AFTER HEPATIC METASTASECTOMY FOR COLORECTAL CANCER

ADAR1 is a promising risk stratification biomarker of remnant liver recurrence after hepatic metastasectomy for colorectal cancer

Abstract Adenosine-to-inosine RNA editing is a process mediated by adenosine deaminases that act on the RNA (ADAR) gene family.It has been discovered recently as an epigenetic modification dysregulated in human cancers.However, the clinical significance of RNA editing in patients with liver metastasis from colorectal cancer (CRC) remains unclear.Th

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Adaptive Fractional-Order Non-Singular Fast Terminal Sliding Mode Control Based on Fixed Time Disturbance Observer for Manipulators

In this study, with the help of a disturbance observer, an adaptive fractional-order sliding mode control scheme click here is designed to achieve trajectory tracking control of indeterminate manipulators.Firstly, the fractional-order non-singular fast terminal sliding mode (FO-NFTSM) surface is presented to increase the convergence velocity of the

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A new mouse model of radiation-induced liver disease reveals mitochondrial dysfunction as an underlying fibrotic stimulus

Background & Aims: High-dose irradiation is an essential tool to help control the growth of hepatic tumors, but it can cause radiation-induced liver disease (RILD).This life-threatening complication manifests itself months following radiation therapy and is characterized by fibrosis of the pericentral sinusoids.In this study, we aimed to establ

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